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Digital Heart-Rate Variability Parameter Monitoring and Assessment ASIC

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6 Author(s)
Massagram, W. ; Dept. of Comput. Sci. & Inf. Technol., Naresuan Univ., Phitsanulok, Thailand ; Hafner, N. ; Mingqi Chen ; Macchiarulo, L.
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This paper describes experimental results for an application-specific integrated circuit (ASIC), designed for digital heart rate variability (HRV) parameter monitoring and assessment. This ASIC chip measures beat-to-beat (RR) intervals and stores HRV parameters into its internal memory in real time. A wide range of short-term and long-term ECG signals obtained from Physionet was used for testing. The system detects R peaks with millisecond accuracy, and stores up to 2 min of continuous RR interval data and up to 4 min of RR interval histogram. The prototype chip was fabricated in a 0.5 ??m complementary metal-oxide semiconductor technology on a 3??3 mm2 die area, with a measured dynamic power consumption of 10 ??W and measured leakage current of 2.62 nA. The HRV monitoring system including this HRV ASIC, an analog-to-digital converter, and a low complexity microcontroller was estimated to consume 32.5 ??V, which is seven times lower power than a stand-alone microcontroller performing the same functions. Compact size, low cost, and low power consumption make this chip suitable for a miniaturized portable HRV monitoring system.

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Biomedical Circuits and Systems, IEEE Transactions on  (Volume:4 ,  Issue: 1 )