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Cooperative OFDM transmission is an efficient solution to combat wireless channel fading and to increase system throughput in future board communication. In this paper, we consider the uplink scenario of a cellular cooperative OFDM network, in which multi-relays can forward the source's message to base station. The uplink throughput is optimized by using decode-and-forward (DF) opportunistic relaying. We show that the problem is formulated as a mixed binary integer programming problem, which is hard to find the global optimum in terms of computational complexity. Thus we decomposed the optimization problem into two sub-problems of opportunistic relaying strategy and power allocation. First, the opportunistic relaying strategy is given by making use of the equivalent channel power gain. Second, a low-complexity power allocation algorithm is proposed. The simulation result shows that the proposed scheme can greatly improve the system throughput.