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Grid technology enables business management resource sharing, and eliminates the phenomenon of island resources. Quality chain is functional value chain of product or service quality forming process. In the paper, quality chain service management by use of grid technology in manufacturing industry is preliminarily studied, and the architecture of quality chain grid is proposed. Then a quality chain life-cycle service management model based on the quality chain grid is constructed. The role of quality chain grid service management is analyzed with a case, which quality chain takes automobile enterprises as the core enterprises, and materials or parts suppliers, retailer and other relevant partners as member enterprises. It explores service management of manufacturing based on grid technology.