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Completed L-measure and Hurst Exponent Based Choquet Integral Predicting Algorithm for Thermostable Proteins

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4 Author(s)
Hsiang-Chuan Liu ; Dept. of Bioinf., Asia Univ., Taichung, Taiwan ; Horng-Jinh Chang ; Yu-Lung Liu ; Yu-Du Jheng

Establishing a good algorithm for predicting temperature of thermostable proteins is an important issue. In this study, an improved thermostable proteins prediction method using Hurst exponent and Choquet integral regression model based on completed L-measure is proposed. The main idea of this method is to integrate the physicochemical properties, fractal property and Choquet integral regression model for amino symbolic sequences with different lengths. For evaluating the performance of this new algorithm, a 5-fold Cross-Validation MSE is performed. Experimental result shows that this new prediction scheme is better than the Choquet integral regression model based on ¿-measure, P-measure and L-measure, respectively and two methods based on Hurst exponent and the traditional prediction models, ridge regression and multiple regression models, respectively.

Published in:

Intelligent Information Technology Application, 2009. IITA 2009. Third International Symposium on  (Volume:2 )

Date of Conference:

21-22 Nov. 2009