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High quality information has an important impact on improving hospital efficiency and patient satisfaction and resolving patient disputes. In this paper, on the basis of the analysis of the research status of information quality and process performance, information quality is considered as an important contribution factor to improve process performance. Then, the research framework and main content are presented. Through the establishment of quantitative information quality indicators, such as correctness, timeliness and completeness, the impact on process performance such as registered queue length, waiting time, utilization of hospital facilities as well as the cost of the treatment process is analyzed from the theoretical aspect, and then it is verified by simulation technology. Finally, the significance and feasibility of this study are clarified.