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Content-based image retrieval is an important research topic in computer vision. MPEG-7 set up a set of standardized description of image contents. By introducing the widely used feature descriptors, we analyze the limitation and deficiency of retrieval methods based on global features in this paper. Meanwhile, an image retrieval approach based on integrated features of regions for MPEG-7 is put forward to meet users' requirements of evaluating similarity on spatial information. The availability of our approach is testified through retrieval experiments. This paper also describes our approach in detail on color quantization, extraction and matching processes of features, and so on.