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With the through application of information technology in international business and logistics, the society raises new demands to the international business professionals, which has directly leaded to a big change in college education system, especially for business schools. In this paper, based on analyzing the achievement made by the e-commerce and logistics laboratory of Shanghai Institute of Foreign Trade, it will show that the framework of international business school experiment and teaching system reach two purposes. On the one hand, it conducts a series of simulations based on the combination with real practices according to increase the comprehensive-skillful experiment and training the students' major practical ability actively. On the other hand, its construction of the cross-disciplinary coordination and innovation correspond with the needs of improving comprehensive quality.