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Spectrofluorimetry is used as an optical assay to investigate whether exposure of bovine serum albumin (BSA) to electromagnetic fields (EMF) causes structural changes in the protein distinct from any caused by heating alone. Such changes would alter the fluorescence spectrum of the BSA, and could indicate a potential for EMF induced altered biological activity of proteins in-vivo. No directly EMF induced fluorescence variations are observed under a 10 minute TETRA burst exposure paradigm at room temperature. An additional structure to the TEM Cell, which increases electric field strength around the cuvette area by a factor of 18, has also been designed.