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Browse Journals & Magazines > Applied Physics Letters ...> Volume:95 Issue:22 Help

Conjugation of quantum dots and Fe3O4 on carbon nanotubes for medical diagnosis and treatment

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12 Author(s)
Shi, Donglu ; Department of Chemical and Materials Engineering, University of Cincinnati, Cincinnati, Ohio 45221, USA ; Cho, Hoon Sung ; Huth, Chris ; Wang, Feng
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Your organization might have access to this article on the publisher's site. To check, click on this link:http://dx.doi.org/+10.1063/1.3268469 

Quantum dots (QDs) and Fe3O4 nanoparticles were conjugated onto the surfaces of carbon nanotubes (CNTs) for medical diagnosis and treatment. The nanoassembly was designed to meet the specific needs in cancer in vivo imaging and simultaneous treatment. The key functionalities needed for clinical applications were integrated, including CNT surface functionalization for attachment of biological molecules in targeting, drug storage capabilities, fluorescent emissions near the infrared range, and magnetic hyperthermia. CNT-QD-Fe3O4 developed exhibited a strong fluorescence near the infrared region for noninvasive optical in vivo imaging. Magnetization measurements showed nearly reversible hysteresis curves from CNT-QD-Fe3O4 nanoassembly. Fe3O4 conjugated CNT was found to experience hyperthermia heating under alternating electromagnetic field.

Published in:
Applied Physics Letters  (Volume:95 ,  Issue: 22 )

Date of Publication: Nov 2009

Page(s):
223702 - 223702-3
ISSN :
0003-6951
Digital Object Identifier :
10.1063/1.3268469
Product Type:
Journals & Magazines
Date of Current Version :
08 December 2009
Issue Date :
Nov 2009

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