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Real-time kinetics measurements of protein induced conformational changes in DNA

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6 Author(s)
Spuhler, P.S. ; Biomed. Eng., Boston Univ., Boston, MA, USA ; Knezevic, J. ; Yalcin, A. ; Droge, P.
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We combine electrical orientation of surface bound dsDNA probes with an optical technique for kinetic measurement of protein-induced conformational changes in DNA. The effects of probe surface density and protein variation are investigated.

Published in:

LEOS Annual Meeting Conference Proceedings, 2009. LEOS '09. IEEE

Date of Conference:

4-8 Oct. 2009