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Linear measurement of polyps in CT colonography using level sets on 3D surfaces

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4 Author(s)
Tan, S. ; Clinical Center, Nat. Inst. of Arthritis & Musculoskeletal & Skin diseases, Bethesda, MD, USA ; Jianhua Yao ; Ward, M.M. ; Summers, R.M.

CT colonography has emerged as a minimally invasive alternative to optical colonoscopy for the screening of polyps which are the precursors to colon cancer. Accurate polyp measurement is crucial as the size of a polyp is considered an indication of its potential for malignancy. We present a novel method for the automatic measurement of polyps. It is based on a level set algorithm capable of evolving on the surface of a 3D object represented by a triangular mesh. It is guided by curvature features and is capable of segmenting the polyp neck, that is, the ridgeline/crestline formed around the polyp by its merging to the colon wall. Our method was validated on 40 polyp surfaces obtained from real clinical data. A 3D manual measurement was used as the reference standard. A correlation of 0.825 was found between polyp measurements from our new method and the reference standard.

Published in:

Engineering in Medicine and Biology Society, 2009. EMBC 2009. Annual International Conference of the IEEE

Date of Conference:

3-6 Sept. 2009