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Nowadays, more and more bioinformatics projects are using distributed computing platform. In distributed systems, cooperation is important to enforce its function. Trust management can establish and maintain cooperation between distributed nodes. In this paper, we explore an adaptive trust management in PDAC model  to help distributed nodes establishing trust relationships. We firstly discuss a reputation tracking scheme that quantifies uncertainty in its rating. We address what is an opinion, how to update opinions after interaction, neighborhood query and interaction protocols in detail. Then we present a prototype system and many experiment results to analyze the performance of this trust model. We claim that this proposed model will accommodate PDAC model and be used in nowadays typical distributed systems for secure cooperation.