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The performance of a nonlinear amplifying loop mirror as a phase-preserving amplitude 2R regenerator in a differential phase-shift-keying transmission system with nonlinear phase noise as dominant limiting effect has been investigated in a recirculating fiber-loop setup. The experimental results show that cascaded regenerators can efficiently prevent the accumulation of nonlinear phase noise in such systems. It was possible to significantly increase the transmission quality; alternatively, a considerable increase of fiber launch power could be achieved for the same bit-error ratio. As a limiting effect, the amplified Rayleigh backscattering in the highly nonlinear fiber is identified when the regenerator is passed multiple times.