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Magnetic particle dosing, release and separation in a microfluidic chip with magnetic actuation

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4 Author(s)
Afshar, R. ; Lab. of Microsyst., Ecole Polytech. Fed. de Lausanne, Lausanne, Switzerland ; Lehnert, T. ; Moser, Y. ; Gijs, M.A.M.

Separation of functionalized magnetic particles or magnetically-labeled entities is an important tool in the field of bioanalysis. We present a novel integrated microfluidic magnetic bead separation device. On-chip manipulation of superparamagnetic beads is performed in a microfluidic channel under the influence of a highly focused magnetic field. Integrated magnetic microtips are used for retaining a defined amount of magnetic particles in a localized plug. This plug is released in a well-controlled way for subsequent particle separation with respect to their size and magnetic volume.

Published in:

Solid-State Sensors, Actuators and Microsystems Conference, 2009. TRANSDUCERS 2009. International

Date of Conference:

21-25 June 2009