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Quantitative immunophenotyping of circulating tumor cells in blood using microfluidic screening chip integrated with hyperspectral microscope

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9 Author(s)
A. P. Horton ; The University of Texas at Austin, USA ; K. Kumar ; H. Liu ; L. Cheng
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An effective screening test for the early diagnosis of cancer is high on the agenda of oncologists, since early detection increases treatment options and patient prognosis. Using microfluidics and Hyperspectral Imaging Microscopy, we demonstrate the ability to capture and immunophenotype circulating tumor cells (CTCs), which are shed by carcinomas at an early stage and signify the presence of cancer in a patient. The technology presented demonstrates the potential for optofluidic microsystems in advanced point-of-care applications and is envisioned to aid disease prognosis, treatment selection, response monitoring, and development of novel therapies.

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TRANSDUCERS 2009 - 2009 International Solid-State Sensors, Actuators and Microsystems Conference

Date of Conference:

21-25 June 2009