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Recently operators of complex systems such as aircraft, power plants, and networks have been emphasizing the need for on-line health monitoring for purposes of maximizing operational availability and safety. The discipline of prognostics and health management (PHM) is being formalized to address the information management and prediction requirements for addressing these needs. Herein, we will explore how standards currently under development within the IEEE can be used to support PHM applications. Particular emphasis will be placed on the role of PHM and PHM-related standards with Department of Defense (DOD) automatic test systems-related research.