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A full-custom regulated two-phase voltage doubler charge pump is presented in this paper. The regulation process is based on the use of a comparator-based pulse-skipping regulator. Since this type of regulation generates an inherent and non-negligible amount of ripple over the regulated output voltage, an on-chip ripple reduction system has been developed and included in the charge pump architecture. Simulated results show that ripple reduction ratios up to 53% can be achieved when the designed ripple reduction solution is applied over a 5 V regulated charge pump with flying and load capacitors Cf=CL=1 uF, switching frequency fs=100 kHz, and load RL=10 KOmega. The proposed design has been implemented using the high-voltage I2T100 0.7mum BCD smart power technology.