By Topic

Potential distribution in three-dimensional periodic myocardium. II. Application to extracellular stimulation

Sign In

Cookies must be enabled to login.After enabling cookies , please use refresh or reload or ctrl+f5 on the browser for the login options.

Formats Non-Member Member
$31 $13
Learn how you can qualify for the best price for this item!
Become an IEEE Member or Subscribe to
IEEE Xplore for exclusive pricing!
close button

puzzle piece

IEEE membership options for an individual and IEEE Xplore subscriptions for an organization offer the most affordable access to essential journal articles, conference papers, standards, eBooks, and eLearning courses.

Learn more about:

IEEE membership

IEEE Xplore subscriptions

4 Author(s)
Krassowska, Wanda ; Dept. of Biomed. Eng. & Pathology, Duke Univ., Durham, NC, USA ; Frazier, D.W. ; Pilkington, T.C. ; Ideker, R.E.

For pt.I see ibid., vol.37, no.3, p.252-66 (1990). Modeling potential distribution in the myocardium treated as a periodic structure implies that activation from high-current stimulation with extracellular electrodes is caused by the spatially oscillating components of the transmembrane potential. This hypothesis is tested by comparing the results of the model with experimental data. The conductivity, fiber orientation, extent of the region, location of the pacing site, and stimulus strength determined from experiments are components of the model used to predict the distributions of potential, potential gradient, and transmembrane potential throughout the region. Assuming that a specific value of the transmembrane potential is necessary and sufficient to activate fully repolarized myocardium, the model provides an analytical relation between large-scale field parameters, such as gradient and current density, and small-scale parameters, such as transmembrane potential.

Published in:

Biomedical Engineering, IEEE Transactions on  (Volume:37 ,  Issue: 3 )