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The design of the RF transmitter for transcutaneous energy transmission is analyzed and experimentally tested. The transmitter consists of a crystal oscillator, a class-E power amplifier, a supply voltage regulator, and a transmitting coil. The transmitting coils made of enameled wire and the receiving coils made on Printed Circuit Board (PCB) were designed simultaneously. In this paper, the compensated methods of transmitting coils and receiving coils are discussed. The topology and working principle of the transmitter are analyzed, the design parameters of the transmitter are calculated. Driven by a crystal oscillator, the class-E power amplifier operates at 13.56 MHz (ISM frequency band). In the conditions of a distance of 10 mm between two coils and 5-9 V DC supply, the voltage measured across the transmitting coil is from 90 V to 130 V, while the voltage across the receiving coil can reach 28 V. The experimental results are in good agreement with the simulating ones. With a distance of 35 mm and a slice of skin between the coils, the receiving voltage reaches still up to 4 V at least, which meets the need of implanted integrated circuits.