Cart (Loading....) | Create Account
Close category search window
 

An Integrative Tool for Gene Regulatory Network Reconstruction Based on Microarray Data

Sign In

Cookies must be enabled to login.After enabling cookies , please use refresh or reload or ctrl+f5 on the browser for the login options.

Formats Non-Member Member
$31 $13
Learn how you can qualify for the best price for this item!
Become an IEEE Member or Subscribe to
IEEE Xplore for exclusive pricing!
close button

puzzle piece

IEEE membership options for an individual and IEEE Xplore subscriptions for an organization offer the most affordable access to essential journal articles, conference papers, standards, eBooks, and eLearning courses.

Learn more about:

IEEE membership

IEEE Xplore subscriptions

5 Author(s)
Ou, J.W. ; Dept. of Comput. Sci., Nat. Tsing Hua Univ., Hsinchu, Taiwan ; Tang, C.Y. ; Hu, R.M. ; Chen, R.M.
more authors

The transcriptional regulation of gene expression has been known to be a key mechanism in the functioning of the cell and the gene expression is influenced by the transcriptional regulatory strengths. In this paper we extend the function of a former proposed gene expression analysis tool named Gene Expression Explorer to include the gene regulatory network reconstruction based on microarray data. The regulatory strengths between transcription factors and genes are implemented by a modified network component analysis method where the genes expression relationships between genes vs. tissues and transcription factors vs. tissues are adopted to explore the regulatory strengths between genes and various transcription factors. Visualized presentation of the proposed tool clearly illustrates the regulatory patterns of transcription factors for each related gene. The biologists could benefit from using this tool to analyze the gene regulatory network based on microarray data.

Published in:

Bioinformatics and BioEngineering, 2009. BIBE '09. Ninth IEEE International Conference on

Date of Conference:

22-24 June 2009

Need Help?


IEEE Advancing Technology for Humanity About IEEE Xplore | Contact | Help | Terms of Use | Nondiscrimination Policy | Site Map | Privacy & Opting Out of Cookies

A not-for-profit organization, IEEE is the world's largest professional association for the advancement of technology.
© Copyright 2014 IEEE - All rights reserved. Use of this web site signifies your agreement to the terms and conditions.