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A biomicrofluidic device and a compact cellular testing system were developed to be used in cancer diagnostics. The device was fabricated by lithography-based microfabrication techniques, followed by two-step etching of deep reactive ion etching, and channels were formed by anodic bonding of Si and Pyrex. The device is based on the capture of cells inside a new meandering weir-type filter design, followed by detection and characterization using specific fluorescent labeling. Breast cancer cells MCF-7 and control cells MCF-10A were flowed through the microfluidic channels, and captured by meandering weir-type filters.