By Topic

Modeling Needle Stimulation of Denervated Muscle Fibers: Voltage–Distance Relations and Fiber Polarization Effects

Sign In

Cookies must be enabled to login.After enabling cookies , please use refresh or reload or ctrl+f5 on the browser for the login options.

Formats Non-Member Member
$33 $13
Learn how you can qualify for the best price for this item!
Become an IEEE Member or Subscribe to
IEEE Xplore for exclusive pricing!
close button

puzzle piece

IEEE membership options for an individual and IEEE Xplore subscriptions for an organization offer the most affordable access to essential journal articles, conference papers, standards, eBooks, and eLearning courses.

Learn more about:

IEEE membership

IEEE Xplore subscriptions

3 Author(s)
Dipl. -Ing. Yvonne Stickler* ; Inst. for Anal. & Sci. Comput., Vienna Univ. of Technol., Vienna, Austria ; Johannes Martinek ; Frank Rattay

A finite-element model of the human thigh was coupled with a 1-D compartment model to simulate the excitation of denervated muscle fibers with a needle electrode. For short electrode-fiber distances, the specific characteristics of the needle geometry determined the areas of lowest threshold values. With increasing distance, these areas shifted toward the needle's center of charge. Comparison of the 1-D model with a 3-D fiber model showed that the assumption of rotational symmetry underlying the 1-D model leads to an overestimation of thresholds. For a 40- mum-diameter fiber stimulated with 50 mus pulses at electrode-fiber distances between 50 mum and 1 mm, the 1-D/3-D threshold ratios were between 1.14 and 1.35 for the muscle fiber model, and between 1.11 and 1.17 for Hodgkin-Huxley membrane properties at 20 degC. For both membrane models, the deviation was more pronounced for large fiber diameters and short stimulation pulses. Qualitative results of the 1-D model like voltage-distance relations and predictions of spike initiation sites were correct.

Published in:

IEEE Transactions on Biomedical Engineering  (Volume:56 ,  Issue: 10 )