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It has been found that a remarkable line structure may be developed on the surface of soda‐lime glass slides by treatment in a hot detergent solution (2% Alconox). The lines are produced by an etching process which exposes ridges or cords of less soluble material that have been introduced into the surface layer by the manufacturing procedure of drawing the glass through an orifice (Fourcault process). Details are given of etch rates, size and distribution of the ridges, and of the effect of annealing treatments. The possibility of the inadvertent production of an anisotropic surface structure is of some importance since soda‐lime microscope slides are frequently used as substrates for vapor deposition processes. Preliminary experiments to examine the effect of the line structure on vapor deposited Permalloy films are discussed.