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This letter derives new gain control schemes for an amplify-and-forward single-frequency relay link in which loop interference from the relay transmit antenna to the relay receive antenna has to be tolerated. The proposed gain control schemes take into account the effect of residual loop interference that remains after imperfect loop interference cancellation. As a result of our gain control strategy, the signal-to-interference and noise ratio can be maximized while, at the same time, transmit power is decreased. Finally, we evaluate system performance by deriving closed-form outage probability expressions for the gain control schemes.