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For some single chip micro computer (MCU) system which work conditions fluctuate seriously, it is necessary to input data and adjusting control parameters by human-computer interface. However, the programs of MCU AT89C51 can not be altered after being programmed into memory. Firstly, the cooperative circuit of AT89C51 and AT24C2 is designed to solve such situation. In addition, a practical system implements precise control by MCU for the read and write operations of the sequential EEPROM chip. Then, the data memorized in AT24C02 are obtained from machine learning and will not lose after power off if altered.