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Multi-Pinhole SPECT Imaging With Silicon Strip Detectors

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4 Author(s)
Peterson, T.E. ; Dept. of Radiol. & Radiol. Sci., Vanderbilt Univ., Nashville, TN ; Shokouhi, S. ; Furenlid, L.R. ; Wilson, D.W.

Silicon double-sided strip detectors offer outstanding instrinsic spatial resolution with reasonable detection efficiency for iodine-125 emissions. This spatial resolution allows for multiple-pinhole imaging at low magnification, minimizing the problem of multiplexing. We have conducted imaging studies using a prototype system that utilizes a detector of 300-micrometer thickness and 50-micrometer strip pitch together with a 23-pinhole collimator. These studies include an investigation of the synthetic-collimator imaging approach, which combines multiple-pinhole projections acquired at multiple magnifications to obtain tomographic reconstructions from limited-angle data using the ML-EM algorithm. Sub-millimeter spatial resolution was obtained, demonstrating the basic validity of this approach.

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Nuclear Science, IEEE Transactions on  (Volume:56 ,  Issue: 3 )