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The effects of thermal neutron irradiation and excess oxygen on the properties of Ti-sheathed MgB2 wires were investigated separately in this paper. No significant influence was observed when thermal neutron irradiation with fluence levels of 1.23 times 1014 and 5.75 times 1014 cm-2 were applied on the sample, while fluence level of 3.16 times 1015 cm-2 provided a strong suppression of in-field critical current density. Excess oxygen in sample preparation process had negative effect on the properties of the MgB2 wires. The samples prepared in air possessed lower critical temperature and in-field current carrying capability in comparison with the sample prepared in glove box.