Cart (Loading....) | Create Account
Close category search window
 

Fokker–Planck analysis of the Langevin–Lorentz equation: Application to ligand-receptor binding under electromagnetic exposure

Sign In

Cookies must be enabled to login.After enabling cookies , please use refresh or reload or ctrl+f5 on the browser for the login options.

Formats Non-Member Member
$31 $31
Learn how you can qualify for the best price for this item!
Become an IEEE Member or Subscribe to
IEEE Xplore for exclusive pricing!
close button

puzzle piece

IEEE membership options for an individual and IEEE Xplore subscriptions for an organization offer the most affordable access to essential journal articles, conference papers, standards, eBooks, and eLearning courses.

Learn more about:

IEEE membership

IEEE Xplore subscriptions

3 Author(s)
Moggia, Elsa ; Department of Biophysical and Electronic Engineering, University of Genoa, via Opera Pia 11a, 16145, Genoa, Italy ; Chiabrera, A. ; Bianco, B.

Your organization might have access to this article on the publisher's site. To check, click on this link:http://dx.doi.org/+10.1063/1.366206 

The statistical properties of the solution of the Langevin–Lorentz equation are analyzed by means of the Fokker–Planck approach. The equation describes the dynamics of an ion that is attracted by a central field and is interacting with a time-varying magnetic field and with the thermal bath. If the endogenous force is assumed to be elastic, then a closed-form expression for the probability density of the process can be obtained, in the case of constant magnetic exposure and, for the time-varying case, at least asymptotically. In the general case, a numerical integration of the resulting set of differential equations with periodically time-varying coefficients has been implemented. A framework for studying the possible effects of low-frequency, low-intensity electromagnetic fields on biological systems has been developed on the basis of the equation. The model assumes that an exogenous electromagnetic field may affect the binding of a messenger attracted by the endogenous force field of its receptor protein. The results are applicable to the analysis of experiments, e.g., exposing a Petri dish, containing a biological sample, to a periodically time-varying magnetic field generated by a pair of Helmholtz coils, most widely used in the scientific literature. The proposed model provides a theoretical mean for evaluating the biological effectiveness of low-frequency, low-intensity electromagnetic exposure. © 1997 American Institute of Physics.

Published in:

Journal of Applied Physics  (Volume:82 ,  Issue: 9 )

Date of Publication:

Nov 1997

Need Help?


IEEE Advancing Technology for Humanity About IEEE Xplore | Contact | Help | Terms of Use | Nondiscrimination Policy | Site Map | Privacy & Opting Out of Cookies

A not-for-profit organization, IEEE is the world's largest professional association for the advancement of technology.
© Copyright 2014 IEEE - All rights reserved. Use of this web site signifies your agreement to the terms and conditions.