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Endoscopic fluorescence detector

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1 Author(s)
Lenz, Peter ; Institut National de la Santé et de la Recherche Médicale, U. 281 (Director D. Cathignol), 151 Cours Albert Thomas, 69003 Lyon, France

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This instrument, working in conjunction with standard clinical endoscopes, detects the fluorescence of hematoporphyrin derivative accumulated in tumors. At the same time, the operator receives a conventional image of the target and a signal indicating the intensity of fluorescence. Owing to the simultaneous measurement of fluorescence and backscattered excitation light as a reference, the dependence of this signal on the target vascularization, the target‐endoscope distance, and the viewing angle is strongly reduced over a wide range of these parameters.

Published in:

Review of Scientific Instruments  (Volume:59 ,  Issue: 6 )