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Endoscopic fluorescence detector

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1 Author(s)
Lenz, Peter ; Institut National de la Santé et de la Recherche Médicale, U. 281 (Director D. Cathignol), 151 Cours Albert Thomas, 69003 Lyon, France

Your organization might have access to this article on the publisher's site. To check, click on this link:http://dx.doi.org/+10.1063/1.1139752 

This instrument, working in conjunction with standard clinical endoscopes, detects the fluorescence of hematoporphyrin derivative accumulated in tumors. At the same time, the operator receives a conventional image of the target and a signal indicating the intensity of fluorescence. Owing to the simultaneous measurement of fluorescence and backscattered excitation light as a reference, the dependence of this signal on the target vascularization, the target‐endoscope distance, and the viewing angle is strongly reduced over a wide range of these parameters.

Published in:

Review of Scientific Instruments  (Volume:59 ,  Issue: 6 )