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Paper deals with industrial realization of feedback control of demanding applications on theirs control, control algorithms and visualization together with real time control from MATLAB/Simulink Environment. Paper shows direct connection and implementation way of designed control schemas of prepared applications to an industrial WinPLC. Described is a way to produce a permanent solution in control applications that are fully prepared, designed and implemented directly from MATLAB/Simulink to the target control platform. As a part, the mentioned solution is using a multiplatform control system REX as a bridge between MATLAB and target platforms. These methods allow minimizing costs of development of control of applications, because it produces target permanent realizations in comparison to classical development methods that usually need expensive real time measurement cards and produce only one purpose development solution.