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The harm of mobile phone radiation to human body is usually divided into two effects which are respectively thermal effect and non-thermal effect. It is evident that the great mass of papers are based on the SAR (Specific Absorption Rate) to investigate all kinds of SAR values including the theoretical and simulated results, using different electromagnetic calculation methods in which FDTD is most popular. The theoretical calculations of SAR make us understand that how the electromagnetic energy from the mobile phone radiation distributes in the human head, but it is hard to validate the authenticity by the way of experiments. If electromagnetism radiation in the microwave frequencies is the same as the ionizing radiation to affect the DNA, result in rupture of the chemical bonds and conduce to the DNA damage, the mobile phone radiation causing cancer will make theory become reality based on the hypothesis about gene mutation inducing cancer. Thus it can be seen that these problems are needed to have more deep studies from the microcosmic domain.