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Manipulation of superparamagnetic beads using on-chip current lines placed on a ferrite magnet

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3 Author(s)
Wang, Z.H. ; Cavendish Laboratory, University of Cambridge, Madingley Road, Cambridge CB3 0HE, United Kingdom ; Lew, W.S. ; Bland, J.A.C.

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Manipulation of superparamagnetic beads in a static solution is demonstrated using on-chip current striplines placed on a ferrite magnet. The ferrite magnet fits the requirement to enhance the bead’s magnetic moment while still keeping beads randomly dispersed in the liquid, so allowing easy and selective manipulation of single beads. By applying currents up to hundreds of milliampere, the tapered stripline first attracts the beads to its edge, then the magnetic force along the edge drives the trapped beads moving continuously towards the chip center. On arriving into the chip central area (a square zone which acts as a site to collect the arriving beads), fine manipulation of selected single beads is further performed by switching on/off and/or tuning the current passing through the nearby quadruple striplines. We suggest that the present system may provide a simple but effective platform for handling magnetic tags for biological and biomedical applications.

Published in:

Journal of Applied Physics  (Volume:99 ,  Issue: 8 )

Date of Publication:

Apr 2006

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