The magnetization reversal of Permalloy (Ni81Fe19) nanowires has been investigated by magneto-optic Kerr effect (MOKE) magnetometry, where one end of the wire exhibits a slope in the thickness. Straight nanowires with a thickness of 7.5 nm, widths of 150 nm, and length of 100 μm were prepared by electron-beam lithography. The sloped ends were achieved by using a penumbra shadow mask during NiFe deposition. The topography of the wires has been studied by atomic force microscopy. One finds that the slope profile can be tuned by the position under the mask, mask-to-sample distance, and angle of deposition. Corresponding MOKE hysteresis loops show a systematic reduction of the coercive field with increasing length of the sloped part. For example, wires where the slope has a length of 45 μm exhibit a coercive field of 11 Oe, whereas nanowires without sloped ends show 107 Oe.