By Topic

Fabrication of elastomer pillar arrays with modulated stiffness for cellular force measurements

Sign In

Cookies must be enabled to login.After enabling cookies , please use refresh or reload or ctrl+f5 on the browser for the login options.

Formats Non-Member Member
$31 $31
Learn how you can qualify for the best price for this item!
Become an IEEE Member or Subscribe to
IEEE Xplore for exclusive pricing!
close button

puzzle piece

IEEE membership options for an individual and IEEE Xplore subscriptions for an organization offer the most affordable access to essential journal articles, conference papers, standards, eBooks, and eLearning courses.

Learn more about:

IEEE membership

IEEE Xplore subscriptions

6 Author(s)
Ghassemi, S. ; Department of Mechanical Engineering, Columbia University, New York, New York 10027 and Nanotechnology Center for Mechanics in Regenerative Medicine, Columbia University, New York, New York 10027 ; Biais, N. ; Maniura, K. ; Wind, S.J.
more authors

Your organization might have access to this article on the publisher's site. To check, click on this link: 

The mechanical properties of a cell’s environment can alter behavior such as migration and spreading, and control the differentiation path of stem cells. Here the authors describe a technique for fabricating substrates whose rigidity can be controlled locally without altering the contact area for cell spreading. The substrates consist of elastomeric pillar arrays in which the top surface is uniform but the pillar height is changed across a sharp step. Preliminary results demonstrate the effects on cell migration and morphology at the step boundary.

Published in:

Journal of Vacuum Science & Technology B: Microelectronics and Nanometer Structures  (Volume:26 ,  Issue: 6 )