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Code-division multiple access (CDMA) technology has been applied to many wireless communication systems. CDMA system suffers from both multiple access interference (MAI) and inter-symbol interference (ISI) over a multipath channel. To suppress MAI and ISI, this paper proposes the spreading codes with interference free windows. In particular, we will develop several upper bounds on the efficiency of generalized spreading codes (for both unitary and complementary codes) in terms of the width of their interference free windows.