High-temperature superconducting HgBa2CaCu2O6+δ films were fabricated on the vicinal surfaces of 4°-miscut SrTiO3 single crystal substrates in a cation-exchange process, with the purpose to induce additional growth defects via a step-flow growth mode on the miscut substrates. The critical current densities (Jc) of these films were measured using a standard four-probe method with magnetic fields applied perpendicular to the film surface. The vicinal Hg-1212 films indeed showed higher Jc’s in magnetic fields and irreversibility fields (Hirr) than that on 0°-cut SrTiO3. Hirr at 77 K is 2.1 T for the film grown 0°-cut SrTiO3, and is enhanced to 2.7 T for the one grown on 4°-miscut SrTiO3. If optimized so that the shape and the density of the defects can be controlled experimentally, this may be a promising way of improve magnetic flux pinning for many practical applications related to coated conductors.