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For nearly two million years, ancient humans lived across Europe, Africa and Asia. They hunted ancient animals, lived short lives, and slowly adapted bigger brains, better minds, and more powerful forms of communication. Then, sometime around 100,000 years ago, something changed. A new way of life began to build, and a major dispersal of genes from ancient Africans carried biological adaptations to this new lifestyle. Living human populations owe most of their ancestry to this ldquoout of Africardquo event.