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Recently there has been a need to incorporate the use of mobile computing devices in hospital or clinical applications, to enhance patient care. The advancement of wireless technology has created unique mechanisms of interaction that can meet the needs of e-health system robustness, reliability and accuracy requirements. This paper presents an interactive wireless medical information system that allows patient instrumentation output data to be accessed and patient details to be entered by medical practitioners using mobile computing devices. We examine mobile and wireless information technology concepts that can be used to interact with a medical information system for controlling real-time data streaming medical instruments.