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Multiscale models of angiogenesis

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5 Author(s)
Qutub, A.A. ; Dept. of Biomed. Eng., Johns Hopkins Univ., Baltimore, MD, USA ; Mac Gabhann, F. ; Karagiannis, E.D. ; Vempati, P.
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This article aims to promote integration of angiogenesis-related models, both integration of the work described herein and many other existing and future models. Integration of molecular mechanisms with cell- and organ- level models allows investigators to study angiogenesis from perspectives in time and space that were once unattainable. As new tools develop for the systematic validation, integration, visualization, and adaptation of these models, the field of angiogenesis heralds an era where modeling becomes an essential component of rigorous experimental design and therapeutic advances.

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Engineering in Medicine and Biology Magazine, IEEE  (Volume:28 ,  Issue: 2 )