Cart (Loading....) | Create Account
Close category search window

Dynamic and Quasi-Static Lung Mechanics System for Gas-Assisted and Liquid-Assisted Ventilation

Sign In

Cookies must be enabled to login.After enabling cookies , please use refresh or reload or ctrl+f5 on the browser for the login options.

Formats Non-Member Member
$31 $13
Learn how you can qualify for the best price for this item!
Become an IEEE Member or Subscribe to
IEEE Xplore for exclusive pricing!
close button

puzzle piece

IEEE membership options for an individual and IEEE Xplore subscriptions for an organization offer the most affordable access to essential journal articles, conference papers, standards, eBooks, and eLearning courses.

Learn more about:

IEEE membership

IEEE Xplore subscriptions

6 Author(s)
Alvarez, F.J. ; Res. Unit in Exp. Pulmonary Physiol., Hosp. of Cruces, Bilbao ; Gastiasoro, E. ; Rey-Santano, M.C. ; Gomez-Solaetxe, M.A.
more authors

Our aim was to develop a computerized system for real-time monitoring of lung mechanics measurements during both gas and liquid ventilation. System accuracy was demonstrated by calculating regression and percent error of the following parameters compared to standard device: airway pressure difference (DeltaPaw), respiratory frequency (fR ), tidal volume (VT), minute ventilation (V'E), inspiratory and expiratory maximum flows (V'ins,max, V'exp,max), dynamic lung compliance (CL,dyn), resistance of the respiratory system calculated by method of Mead-Whittenberger (Rrs,MW) and by equivalence to electrical circuits (Rrs,ele), work of breathing (WOB), and overdistension. Outcome measures were evaluated as function of gas exchange, cardiovascular parameters, and lung mechanics including mean airway pressure (mPaw). DeltaPaw, VT, V'ins,max, V'exp,max, and V'E measurements had correlation coefficients r = 1.00, and %error < 0.5%. fR, CL,dyn, Rrs,MW, Rrs,ele, and WOB showed r ges 0.98 and %error < 5%. Overdistension had r = 0.87 and %error < 15%. Also, resistance was accurately calculated by a new algorithm. The system was tested in rats in which lung lavage was used to induce acute respiratory failure. After lavage, both gas- and liquid-ventilated groups had increased mPaw and WOB, with decreased VT, V'E, CL,dyn, Rrs,MW, and Rrs,ele compared to controls. After 1-h ventilation, both injured group had decreased VT, V'E, and CL,dyn, with increased mPaw, Rrs,MW, Rrs,ele, and WOB. In lung-injured animals, liquid ventilation restored gas exchange, and cardiovascular and lung function- - s. Our lung mechanics system was able to closely monitor pulmonary function, including during transitions between gas and liquid phases.

Published in:

Biomedical Engineering, IEEE Transactions on  (Volume:56 ,  Issue: 7 )

Date of Publication:

July 2009

Need Help?

IEEE Advancing Technology for Humanity About IEEE Xplore | Contact | Help | Terms of Use | Nondiscrimination Policy | Site Map | Privacy & Opting Out of Cookies

A not-for-profit organization, IEEE is the world's largest professional association for the advancement of technology.
© Copyright 2014 IEEE - All rights reserved. Use of this web site signifies your agreement to the terms and conditions.