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Inexpensive, universal serial bus-powered and fully portable lab-on-a-chip-based capillary electrophoresis instrument

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8 Author(s)
Kaigala, G.V. ; Dept. of Electr. & Comput. Eng., Univ. of Alberta, Edmonton, AB ; Behnam, M. ; Bliss, C. ; Khorasani, M.
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Capillary electrophoresis is a cornerstone of lab-on-a-chip (LOC) implementations for medical diagnostics. However, the infrastructure needed to operate electrophoretic LOC implementations tends to be large and expensive, hindering the development of portable or low-cost systems. A custom-designed and highly integrated microelectronic chip for high-voltage generation switching and interfacing is recently developed. Here, the authors integrate the microelectronic chip with a microfluidic chip, a solid-state laser, filter, lens and several dollars worth of electronic components to form an inexpensive and portable platform, which is the size of a mobile telephone. This compact system has such reduced power requirements that the complete platform can be operated using a universal serial bus link to a computer. It is believed that this system represents a significant advancement in practical LOC implementations for point-of-care medical diagnostics.

Published in:

Nanobiotechnology, IET  (Volume:3 ,  Issue: 1 )

Date of Publication:

March 2009

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