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Many services of 4G mobile communication are important applications of pervasive computing. Adaptive Beamforming and V-blast are both advanced technologies of 4G mobile communication. In the paper, a new communication scheme with adaptive beamforming is proposed for the uplink of cellular system with vertical bell laboratories layered space-time (V-BLAST) coding. The proposed scheme performs adaptive beamforming processing which could effectively suppress cochannel interference (CCI) to ensure the communication quality of the V-BLAST system. Simulation results show that the scheme could achieve good performance in cellular system with CCI. It means the users of mobile communication could get better service automatically with nothing else to do.