Cart (Loading....) | Create Account
Close category search window
 

Convex optimization of coincidence time resolution for high resolution PET systems

Sign In

Cookies must be enabled to login.After enabling cookies , please use refresh or reload or ctrl+f5 on the browser for the login options.

Formats Non-Member Member
$31 $13
Learn how you can qualify for the best price for this item!
Become an IEEE Member or Subscribe to
IEEE Xplore for exclusive pricing!
close button

puzzle piece

IEEE membership options for an individual and IEEE Xplore subscriptions for an organization offer the most affordable access to essential journal articles, conference papers, standards, eBooks, and eLearning courses.

Learn more about:

IEEE membership

IEEE Xplore subscriptions

5 Author(s)
Reynolds, Paul D. ; Department of Electrical Engineering, Stanford University, CA 94305 USA ; Olcott, Peter D. ; Pratx, G. ; Lau, Frances W.Y.
more authors

We are developing a dual panel breast-dedicated PET system using NOVA RENA-3 ASICs. The coincidence timing resolution of the RENA-3 ASIC can be improved with list mode calibration. We treat the calibration problem as a convex optimization problem and use the RENA-3’s analog based timing system to correct the measured data for time dispersion effects from correlated noise, position sensitive avalanche photodiode (PSAPD) signal delays and varying signal amplitudes. The direct solution to the optimization problem involves a matrix inversion that grows order (n2) with the number of parameters. An iterative method using single-coordinate descent to approximate the inversion grows only order (n). The system calibration method is demonstrated with measured pulser data as well as with two LSO-PSAPD detectors in electronic coincidence. After applying the algorithm, the 511keV photopeak paired coincidence time resolution from the LSO-PSAPD detectors under study improved by 57%, from raw value of 16.3±0.07 ns FWHM to 6.92±0.02 ns FWHM (11.52±0.05 ns to 4.89±0.02 ns for unpaired photons).

Published in:

Nuclear Science Symposium Conference Record, 2008. NSS '08. IEEE

Date of Conference:

19-25 Oct. 2008

Need Help?


IEEE Advancing Technology for Humanity About IEEE Xplore | Contact | Help | Terms of Use | Nondiscrimination Policy | Site Map | Privacy & Opting Out of Cookies

A not-for-profit organization, IEEE is the world's largest professional association for the advancement of technology.
© Copyright 2014 IEEE - All rights reserved. Use of this web site signifies your agreement to the terms and conditions.