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Grids are increasingly being used in applications, one of which is e-learning. As most of business and academic institutions (universities) and training centres around the world have adopted this technology in order to create, deliver and manage their learning materials through the Web, the subject has become the focus of investigate. Still, collaboration between these institutions and centres is limited. Existing technologies such as grid, Web services and agents are promising better results. In this paper we support building our architecture Regionally Distributed Architecture for Dynamic e-Learning Environment (RDADeLE) by using agent technology (Multi-Agent System) using Java Agent DEvelopment Framework (JADE). By describing these agents in details, we prove that agents can be implemented to work well to extend the autonomy and interoperability for regional data grid.