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A new pub/sub/query (PSQ) paradigm has been developed for the information management of high performance computers. The main advantage of PSQ over Message Passing Interface (MPI) is the ability to adapt to dynamically changing requirements. Information management for high performance computing (HPC) applications also coordinates the distribution of data across processing nodes, both for initial data and for intermediate results distribution. Additionally, PSQ exhibits enhanced robustness. A matrix multiplication case study illustrates the advantages of the PSQ software development approach.