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With development of cardiac electrophysiology and computing power, various biophysically detailed computer models of cardiac electrical activity have been developed to simulate the electrical activities of cardiac systems at cellular, tissue and organ levels. In this study, we developed a modelling and simulation platform for electrical activities of cardiac cells (Si-PEAC) with aims to provide a user-friendly interface to study the ionic mechanisms underlying the genesis of cardiac electrical action potentials under various physiological and pathological conditions. The effectiveness of system is validated by editing and testing several popular cell models.
Computers in Cardiology, 2008
Date of Conference: 14-17 Sept. 2008