By Topic

Model-based estimation of cardiac output and total peripheral resistance

Sign In

Cookies must be enabled to login.After enabling cookies , please use refresh or reload or ctrl+f5 on the browser for the login options.

Formats Non-Member Member
$31 $13
Learn how you can qualify for the best price for this item!
Become an IEEE Member or Subscribe to
IEEE Xplore for exclusive pricing!
close button

puzzle piece

IEEE membership options for an individual and IEEE Xplore subscriptions for an organization offer the most affordable access to essential journal articles, conference papers, standards, eBooks, and eLearning courses.

Learn more about:

IEEE membership

IEEE Xplore subscriptions

4 Author(s)
Parlikar, T.A. ; Massachusetts Inst. of Technol., Cambridge, MA ; Heldt, T. ; Ranade, G.V. ; Verghese, G.C.

We describe a novel model-based approach to estimate cardiac output (CO) and total peripheral resistance (TPR) continuously from peripheral arterial blood pressure (ABP) waveforms. Our method exploits the intra-beat and inter-beat variability in ABP to estimate the lumped time constant of a beat-to-beat averaged Windkessel model of the arterial tree, from which we obtain an uncalibrated estimate of CO. To estimate absolute CO, we determine the lumped arterial compliance using calibration data, and assuming either constant or state-dependent compliance. We applied our method to a porcine data set in which stroke volume was measured with an ultrasonic flowmeter. We obtain root-mean-square normalized errors of 11-13% across all pigs, lower than those obtained on the same data set using various other estimation methods. The CO estimates, and TPR estimates derived from them track intravenous drug infusions quite closely.

Published in:

Computers in Cardiology, 2007

Date of Conference:

Sept. 30 2007-Oct. 3 2007