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As a parametric amplified noise, nonlinear phase noise limits the channel capacity in multispan fiber-optics transmissions. In this paper, the reduction of nonlinear phase noise by use of Wiener filtering is studied. Extracting signal from time-domain concepts, parametric amplified noise covering signal spectrum in frequency domain can be suppressed considerably. Timing jitter and ghost pulses due to intrachannel nonlinearities can also be compensated. Nonparametric Wiener filtering is used at the end of six configurations of dispersion compensation (DC) transmission lines: pre- and postlumped DC, distributed DC without optical phase conjugation (OPC), dispersion inversion (DI) about midlink OPC with, respectively, one-for-multispan, single type span and alternate type span on each side of OPC. It is found that single-DI and alternate-DI schemes have higher input power capacity than one-for-multi-DI scheme. Further reductions in the nonlinear phase noise accumulation for all these DC maps are obtained with Wiener filtering, and higher absolute dispersion can decrease signal fluctuation due to nonlinear phase noise, as well.