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Software system for biological signal processing and risk evaluation in pediatrics

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4 Author(s)
Ayala, D.E. ; ETSI Telecomunicacion, Santiago Univ., Vigo, Spain ; Hermida, R.C. ; Fernandez, J.R. ; Garcia, L.

The serum gastrin (GT) data from 18 children were coded and analyzed on a minicomputer by linear least-squares procedures. Circadian rhythm parameters were computed for each individual series by the single cosinor fit of a 24-h cosine curve. The analysis of those data reveals a statistically significant circadian rhythm as the principal spectral feature. A circadian parameter comparison of data from the two genders indicates a similar MESOR (midline-estimating statistic of rhythm M ; P=0.308), amplitude (A; P=0.523) and acrophase (Φ; P=0.485) for both groups. It is concluded that the assessment of chronobiologic characteristics of GT and other related variables by a properly designed software system refines and renders rigorous any biomedical comparison, e.g. for groups of children, whether one's interest relates to gender, age, ethnicity, or the risk of developing diseases

Published in:

Computer-Based Medical Systems,1989. Proceedings., Second Annual IEEE Symposium on

Date of Conference:

26-27 Jun 1989