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This paper deals with an analysis of techniques of interleaved Echo-Planar imaging (EPI) method for Functional Magnetic Resonance Imaging (fMRI). In order to have optimum echo time and consequently achieving low image distortion, an approach has been emphasized upon a technique that acquires six images, each with a different echo time, in a single shot. Also investigation has been initiated for the feasibility and pragmatism of this technique. Techniques of reduction of image artifact and Nyquist or N/2ghost are compared for effectiveness on fMRI data sets are also demonstrated. Again this approach focused on the benefits and problems of interleaved EPI system.